A Paul Graham essay from last November that is truly worth revisiting on a periodic basis. Perhaps now more than ever though:
The three components of independent-mindedness work in concert: fastidiousness about truth and resistance to being told what to think leave space in your brain, and curiosity finds new ideas to fill it.
The idea of being open-minded but skeptical but almost above all to be curious is a fantastic code to live by. Really like this bit, "unfashionable ideas are disproportionately likely to lead somewhere interesting. The best place to find undiscovered ideas is where no one else is looking."